If you have COPD associated with chronic bronchitis, ADVAIR 250/50 may help.

ADVAIR v/orks differently than other COPD medications. It is the only product with an anti-inflammatory and a

bronchodilator working together to help improve lung function. Talk to your doctor and find out if ADVAIR is right for you.

ADVAIR

helps significantly improve

lung function so you

can

breathe

better.*

It is not known how anti-inflammatories work in COPD.

Important Information:

ADVAIR DISKUS 250/50 is approved for controlling symptoms and preventing wheezing in adults with COPD associated with chronic

bronchitis. The benefit of using ADVAIR DISKUS for longer than 6 months has not been evaluated. You should only take 1 inhalation of ADVAIR DISKUS

250/50 twice a day. Taking higher doses will not provide additional benefits but may increase your chance of certain side effects. Patients with COPD taking

ADVAIR DISKUS may have a higher chance of pneumonia. Call your doctor if you notice any of the following symptoms: change in amount or color of sputum,

fever, chills, increased cough, or increased breathing problems. Patients at risk for developing bone loss (osteoporosis) and some eye problems (cataracts

or glaucoma) should be aware that use of inhaled corticosteroids, including ADVAIR DISKUS. may increase your risk. You should consider having regular eye

exams. ADVAIR DISKUS does not replace fast-acting inhalers for acute symptoms.

Measured by a breathing test in people taking ADVAIR 250/50. compared with people taking either fluticasone propionate 250 meg or salmeterol 50 meg.

Maximum effects may take several weeks. Your results may vary.

See advairCOPD.com for eligibility rules.

Please see accompanying important information about ADVAIR DISKUS 250/50.

You are encouraged to report negative side effects of prescription drugs to the FDA

Visitwww.fda.gov/medwatch. or call 1-800-FDA-1088.

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